EGCG: The Powerful Polyphenol in Green Tea that May Help Prevent Cancer
Green tea is one of the most popular beverages in the world, and for good reasons. Not only does it taste great and refresh your mind, but it also contains a variety of health-promoting compounds, especially polyphenols. Polyphenols are natural antioxidants that can protect your cells from oxidative stress and inflammation, which are linked to many chronic diseases, including cancer.
Among the polyphenols in green tea, epigallocatechin gallate (EGCG) is the most abundant and potent. EGCG has been extensively studied for its anticancer effects, both in laboratory and clinical settings. In this blog, we will explore how EGCG may help reduce cancer risk by modulating different aspects of cancer biology.
➟ How Recent research Suggests EGCG May Help Reduce Cancer Risk
Cancer is a complex disease that involves the uncontrolled growth and spread of abnormal cells. There are many factors that can contribute to the development and progression of cancer, such as genetic mutations, environmental toxins, hormonal imbalances, and chronic inflammation. EGCG may help prevent cancer by interfering with these factors and targeting multiple pathways that are essential for cancer growth. Here are some of the mechanisms by which EGCG may exert its anticancer effects:
Green tea is a popular drink that has many health benefits, especially for preventing cancer. This is because green tea contains antioxidants called catechins, which can protect your cells from damage and inflammation. The most powerful catechin in green tea is epigallocatechin-3-gallate (EGCG), which can interfere with various factors that contribute to cancer development and progression, such as:
- Drug resistance: EGCG can increase the uptake and decrease the efflux of chemotherapy drugs in cancer cells, making them more effective (1).
- Cell death: EGCG can trigger apoptosis and autophagy, two processes that cause cancer cells to self-destruct23.
- Cell cycle: EGCG can stop cancer cells from dividing uncontrollably by blocking the proteins that regulate the cell cycle.
- Angiogenesis: EGCG can prevent cancer cells from forming new blood vessels, which they need to grow and spread.
- Metastasis: EGCG can reverse the changes that make cancer cells more invasive and mobile, such as epithelial-mesenchymal transition (EMT).
- Epigenetics: EGCG can alter the expression of genes that are involved in cancer, such as tumor suppressors and oncogenes.
➟ How to Consume EGCG
To get the most benefits from green tea, you should drink 3 to 10 cups a day, depending on your body weight and metabolism. However, if you find it hard to drink that much, you can try effervescent green tea tablets, which are more convenient and potent than regular green tea. Effervescent green tea tablets are made from organic Japanese matcha, which has higher levels of EGCG and other antioxidants than other types of green tea. Effervescent green tea tablets also have other advantages, such as:
- Better absorption: Effervescent green tea tablets dissolve in water, creating a fizzy drink that is easier to digest and absorb than solid tablets or capsules.
- Faster action: Effervescent green tea tablets deliver the antioxidants to your bloodstream faster than regular green tea, which has to go through the digestive system first.
- Enhanced flavor: Effervescent green tea tablets have a natural lemon flavor, which masks the bitterness and astringency of green tea, making it more enjoyable to drink.
Green tea is a simple and delicious way to boost your health and lower your cancer risk. Whether you prefer regular green tea or effervescent green tea tablets, you can benefit from the powerful effects of EGCG and other antioxidants. Cheers! 🍵
➟ References
- cmbl.biomedcentral.com
- mdpi.com
- verywellhealth.com
- bmcgenomics.biomedcentral.com
- healthline.com
- doi.org
- en.wikipedia.org